Genetic factors contribute significantly to the risk to develop an aortic aneurysm and/or dissection. Genetic syndromes that affect connective tissue, such as Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome vascular type, and Turner syndrome, put individuals at a significantly increased risk to develop an aortic aneurysm and/or dissection.

In addition, individuals may have a hereditary (or genetic) predisposition to develop an aortic aneurysm and/or dissection even without having one of these genetic syndromes. First-degree relatives (parents, siblings, children) of a person who has, or has had, a thoracic aortic aneurysm and/or dissection have a higher chance to develop an aneurysm.

To learn more about the genetics of aortic aneurysms and dissections, visit The John Ritter Research Program in Aortic and Vascular Diseases:

To contact the lab please email:  
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